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CryoMaestro overview

CryoMaestro is a private operating environment for cryo-EM facilities. It keeps the physical sample, instrument plan, acquired data, processing history, and operational record connected instead of splitting them across unrelated applications and spreadsheets.

  1. Facility intake — projects, users, shipments, dewars, pucks, boxes, samples, and grids.
  2. Scheduling — instrument bookings, access, ownership, and session preparation.
  3. Microscope workspace — status, presets, calibrations, acquisition plans, targets, and run monitoring.
  4. Live quality feedback — early motion, CTF, ice, contamination, picking, and classification signals.
  5. Processing and analysis — session processing, cross-session workspaces, saved workflows, jobs, and results.
  6. Operations — utilization, throughput, instrument health, compute activity, and provenance.

CryoMaestro models the relationships that matter: a project contains samples and grids; a grid enters a session; a session produces targets and exposures; each processing result points back to its inputs, settings, and acquisition context. That connected record is what makes handoffs inspectable.

  • Facility administrators configure access, instruments, integrations, policies, and review gates.
  • Microscope operators prepare sessions, review preflight state, supervise runs, and respond to warnings.
  • Researchers follow their samples, inspect results, and work in assigned projects and analysis spaces.
  • Methods teams propose extensions through the documented review process.
Research and facility use

CryoMaestro is not a medical device or a certified instrument-safety system. A trained operator must validate each deployment and remain responsible for live instrument operation. Read the Research-Use Notice before connecting an instrument.

Continue with First session for the operator workflow, or Deployment and onboarding if you are preparing a facility installation.